Royal Air Force Typhoon jets have joined forces with France's air force in a coordinated attack targeting an hidden munitions depot in Syrian territory used by the IS group, according to the UK Ministry of Defence.
The facility, pinpointed through intelligence, was believed to be housing weapons and explosive materials, the announcement noted, and was situated in hills just to the north of the ancient city of Palmyra in central Syria.
"Our aircraft used Paveway IV guided bombs to hit a several entry passages leading to the depot... preliminary assessments suggest the target was engaged successfully," officials stated.
There was no evidence of any civilian casualties in the operation on Saturday evening and all the aircraft returned safely, the defence officials confirmed.
The Typhoon FGR4s were assisted by a Voyager aerial refuelling aircraft.
Daesh - referred to as the so-called Islamic State - established jihadist rule over large swathes of Syria and Iraq until 2019.
"This operation shows British leadership, and determination to stand shoulder to shoulder with our partners, to eliminate any revival of IS and their violent and radical beliefs in the Middle East," UK Defence Secretary the minister stated.
British military aircraft have carried out surveillance missions over Syrian airspace to "forestall any attempted comeback" of IS subsequent to its defeat at the Baghuz confrontation in 2019, the ministry said.
"I extend gratitude to every member of British forces participating in this strike for their professionalism and their bravery," he said. "They were among a great many British troops deployed over the holidays. This mission, to take out militants who endanger our way of life, highlights how British military are always on standby, throughout the year, protecting the UK at home and powerful internationally."
During December, the United States armed forces carried out what it termed a "major assault" targeting Islamic State objectives in Syria, following an attack resulted in the deaths of two US servicemembers and a civilian interpreter in the Palmyra area.
The UN estimates IS still maintains between 5,000 and 7,000 combatants in Iraq and Syria.